MOTS-c: Sourcing, Purity, and Verification Standards
How SpartaLabs sources, tests, and verifies MOTS-c for research applications. Educational reference.

Mitochondrial-derived 16-amino-acid peptide. Lyophilized.
In Stock
MOTS-C is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA region of the mitochondrial genome.
The peptide is studied in preclinical literature as a reference compound in research on mitochondrial-nuclear retrograde signalling and AMPK-pathway activation.
Lyophilized under inert atmosphere. Reconstitute with sterile bacteriostatic water; store reconstituted samples refrigerated. For laboratory and research use only. Not for human or veterinary use.
Every batch of MOTS-C is independently tested by a third-party laboratory. Certificates of Analysis include HPLC purity testing, mass spectrometry confirmation, and sterility verification.
Contact us at info@spartalabs.net to request the COA for this product.
Orders are processed within 1–2 business days. Standard shipping typically takes 3–5 business days within the continental United States.
All products are shipped in temperature-controlled, discreet packaging to ensure product integrity.
MOTS-C is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA region of the mitochondrial genome.
The peptide is studied in preclinical literature as a reference compound in research on mitochondrial-nuclear retrograde signalling and AMPK-pathway activation.
Lyophilized under inert atmosphere. Reconstitute with sterile bacteriostatic water; store reconstituted samples refrigerated. For laboratory and research use only. Not for human or veterinary use.
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How SpartaLabs sources, tests, and verifies MOTS-c for research applications. Educational reference.
A bibliographic summary of peer-reviewed research on MOTS-c, covering preclinical models of metabolic signaling, nuclear gene regulation, skeletal muscle biology, and circulating peptide levels in human observational studies. Educational reference.
MOTS-c is a 16-amino-acid peptide encoded within mitochondrial DNA—one of a growing class of mitochondrial-derived peptides investigated for their roles in cellular energy signaling. Educational reference.
Published research has characterized MOTS-c as a mitochondrial-encoded peptide that modulates intracellular metabolic signaling through the folate-AICAR-AMPK axis and participates in mitochondrial-to-nuclear retrograde communication. Educational reference.
MOTS-c was identified in 2015 through systematic interrogation of mitochondrial open reading frames at the University of Southern California. This article traces the peptide's discovery, the scientific lineage that enabled it, and its subsequent research and regulatory context. Educational reference.
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